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Anemarrhena asphodeloides Non-Steroidal Saponin Components Alter the Pharmacokinetic Profile of Its Steroidal Saponins in Rat

A rapid, selective and sensitive UPLC-MS/MS assay was established to determine the plasma concentrations of four steroidal saponins. Sprague-Dawley rats were allocated to four groups which were orally administered Anemarrhena asphodeloides extracts (ASE), ASE combined with macromolecular fraction (A...

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Detalles Bibliográficos
Autores principales: Tang, Zhishu, Li, Guolong, Yang, Jie, Duan, Jinao, Qian, Dawei, Guo, Jianming, Zhu, Zhenhua, Song, Zhongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331991/
https://www.ncbi.nlm.nih.gov/pubmed/26132904
http://dx.doi.org/10.3390/molecules200711777