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Generation of Aptamers with an Expanded Chemical Repertoire

The enzymatic co-polymerization of modified nucleoside triphosphates (dN*TPs and N*TPs) is a versatile method for the expansion and exploration of expanded chemical space in SELEX and related combinatorial methods of in vitro selection. This strategy can be exploited to generate aptamers with improv...

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Detalles Bibliográficos
Autores principales: Diafa, Stella, Hollenstein, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332006/
https://www.ncbi.nlm.nih.gov/pubmed/26389865
http://dx.doi.org/10.3390/molecules200916643