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Sensitive and Rapid UHPLC-MS/MS for the Analysis of Tomato Phenolics in Human Biological Samples

An UHPLC-MS/MS method for the quantification of tomato phenolic metabolites in human fluids was optimized and validated, and then applied in a pilot dietary intervention study with healthy volunteers. A 5-fold gain in speed (3.5 min of total run); 7-fold increase in MS sensitivity and 2-fold greater...

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Detalles Bibliográficos
Autores principales: Martínez-Huélamo, Miriam, Tulipani, Sara, Jáuregui, Olga, Valderas-Martinez, Palmira, Vallverdú-Queralt, Anna, Estruch, Ramón, Torrado, Xavier, Lamuela-Raventós, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332008/
https://www.ncbi.nlm.nih.gov/pubmed/26580589
http://dx.doi.org/10.3390/molecules201119702