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Role of Polymeric Excipients in the Stabilization of Olanzapine when Exposed to Aqueous Environments
Hydrate formation is a phase transition which can occur during manufacturing processes involving water. This work considers the prevention of hydration of anhydrous olanzapine and hydrate conversions in the presence of water and polymers (polyethyleneglycol; hydroxypropylcellulose; polyvinylpyrrolid...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332009/ https://www.ncbi.nlm.nih.gov/pubmed/26703534 http://dx.doi.org/10.3390/molecules201219832 |