Ascorbic Acid-Initiated Tandem Radical Cyclization of N-Arylacrylamides to Give 3,3-Disubstituted Oxindoles

An ascorbic acid-promoted and metal-free tandem room temperature cyclization of N-arylacrylamides with 4-nitrobenzenediazonium generated in situ was developed. This reaction proceeds smoothly through a radical mechanism and provides an environmentally friendly alternative approach to biologically ac...

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Detalles Bibliográficos
Autores principales: Liu, Sheng, Cheng, Pi, Liu, Wei, Zeng, Jian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332015/
https://www.ncbi.nlm.nih.gov/pubmed/26343622
http://dx.doi.org/10.3390/molecules200915631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332015/
https://www.ncbi.nlm.nih.gov/pubmed/26343622
http://dx.doi.org/10.3390/molecules200915631

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