Synthesis, Molecular Structure, Metabolic Stability and QSAR Studies of a Novel Series of Anticancer N-Acylbenzenesulfonamides

A series of novel N-acyl-4-chloro-5-methyl-2-(R(1)-methylthio)benzenesulfonamides 18–47 have been synthesized by the reaction of N-[4-chloro-5-methyl-2-(R1-methylthio)benzenesulfonyl]cyanamide potassium salts with appropriate carboxylic acids. Some of them showed anticancer activity toward the human...

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Detalles Bibliográficos
Autores principales: Żołnowska, Beata, Sławiński, Jarosław, Belka, Mariusz, Bączek, Tomasz, Kawiak, Anna, Chojnacki, Jarosław, Pogorzelska, Aneta, Szafrański, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332020/
https://www.ncbi.nlm.nih.gov/pubmed/26506328
http://dx.doi.org/10.3390/molecules201019101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332020/
https://www.ncbi.nlm.nih.gov/pubmed/26506328
http://dx.doi.org/10.3390/molecules201019101

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