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Comparative Anticonvulsant Study of Epoxycarvone Stereoisomers

Stereoisomers of the monoterpene epoxycarvone (EC), namely (+)-cis-EC, (−)-cis-EC, (+)-trans-EC, and (−)-trans-EC, were comparatively evaluated for anticonvulsant activity in specific methodologies. In the pentylenetetrazole (PTZ)-induced anticonvulsant test, all of the stereoisomers (at 300 mg/kg)...

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Detalles Bibliográficos
Autores principales: Salgado, Paula Regina Rodrigues, da Fonsêca, Diogo Vilar, Braga, Renan Marinho, de Melo, Cynthia Germoglio Farias, Andrade, Luciana Nalone, de Almeida, Reinaldo Nóbrega, de Sousa, Damião Pergentino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332048/
https://www.ncbi.nlm.nih.gov/pubmed/26528962
http://dx.doi.org/10.3390/molecules201119649