Cargando…

Synthesis and Preliminary Biological Evaluation of 1,3,5-Triazine Amino Acid Derivatives to Study Their MAO Inhibitors

Three series of 4,6-dimethoxy-, 4,6-dipiperidino- and 4,6-dimorpholino-1,3,5-triazin-2-yl) amino acid derivatives were synthesized and characterized. A preliminary study for their monoamine oxidase inhibitory activity showed that compounds 7, 18, and 25 had MAO-A inhibition activity comparable to th...

Descripción completa

Detalles Bibliográficos
Autores principales: Khattab, Sherine N., Khalil, Hosam H., Bekhit, Adnan A., El-Rahman, Mohamed Mokbel Abd, El-Faham, Ayman, Albericio, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332092/
https://www.ncbi.nlm.nih.gov/pubmed/26364629
http://dx.doi.org/10.3390/molecules200915976