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Development of Radiolabeled Membrane Type-1 Matrix Metalloproteinase Activatable Cell Penetrating Peptide Imaging Probes

Membrane type-1 matrix metalloproteinase (MT1-MMP or MMP-14) plays an important role in adverse cardiac remodelling. Here, we aimed to develop radiolabeled activatable cell penetrating peptides (ACPP) sensitive to MT1-MMP for the detection of elevated MT1-MMP levels in adverse cardiac remodelling. T...

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Detalles Bibliográficos
Autores principales: van Duijnhoven, Sander M. J., Robillard, Marc S., Nicolay, Klaas, Grüll, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332093/
https://www.ncbi.nlm.nih.gov/pubmed/26147581
http://dx.doi.org/10.3390/molecules200712076