Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to the Presence of Cholesterol

In the present investigation we studied the molecular mechanisms of the monodesmosidic saponin digitonin on natural and artificial membranes. We measured the hemolytic activity of digitonin on red blood cells (RBCs). Also different lipid membrane models (large unilamellar vesicles, LUVs, and giant u...

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Detalles Bibliográficos
Autores principales: Sudji, Ikhwan Resmala, Subburaj, Yamunadevi, Frenkel, Nataliya, García-Sáez, Ana J., Wink, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332127/
https://www.ncbi.nlm.nih.gov/pubmed/26569199
http://dx.doi.org/10.3390/molecules201119682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332127/
https://www.ncbi.nlm.nih.gov/pubmed/26569199
http://dx.doi.org/10.3390/molecules201119682

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