Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells

Foam cell formation as a result of imbalance of modified cholesterol influx and efflux by macrophages is a key to the occurrence and development of atherosclerosis. Oxidative stress is thought to be involved in the pathogenesis of atherosclerosis. SS-31 is a member of the Szeto-Schiller (SS) peptide...

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Detalles Bibliográficos
Autores principales: Hao, Shuangying, Ji, Jiajie, Zhao, Hongting, Shang, Longcheng, Wu, Jing, Li, Huihui, Qiao, Tong, Li, Kuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332157/
https://www.ncbi.nlm.nih.gov/pubmed/26633327
http://dx.doi.org/10.3390/molecules201219764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332157/
https://www.ncbi.nlm.nih.gov/pubmed/26633327
http://dx.doi.org/10.3390/molecules201219764

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