Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity

Six novel imidazoline derivatives were synthesized and tested in antifungal assays. One of the compounds, N-cyclohexyl-2-imino-3-(4-nitrophenyl)imidazolidine-1-carboxamide showed moderate activity against several clinical strains of Candida albicans. Its structure was solved by X-ray crystallography...

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Detalles Bibliográficos
Autores principales: Wróbel, Tomasz M., Kosikowska, Urszula, Kaczor, Agnieszka A., Andrzejczuk, Sylwia, Karczmarzyk, Zbigniew, Wysocki, Waldemar, Urbańczyk-Lipkowska, Zofia, Morawiak, Maja, Matosiuk, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332182/
https://www.ncbi.nlm.nih.gov/pubmed/26287137
http://dx.doi.org/10.3390/molecules200814761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332182/
https://www.ncbi.nlm.nih.gov/pubmed/26287137
http://dx.doi.org/10.3390/molecules200814761

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