Novel Penicillin-Type Analogues Bearing a Variable Substituted 2-Azetidinone Ring at Position 6: Synthesis and Biological Evaluation

The synthesis and the biological activity of novel semi-synthetic β-lactam compounds containing an azetidinone moiety joined to the amino-nitrogen of the (+)-6-aminopenicillanic acid (6-APA) as new antibacterial agents is reported. The synthesized compounds were screened for their in vitro antimicro...

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Detalles Bibliográficos
Autores principales: De Rosa, Margherita, Vigliotta, Giovanni, Palma, Giuseppe, Saturnino, Carmela, Soriente, Annunziata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332199/
https://www.ncbi.nlm.nih.gov/pubmed/26690391
http://dx.doi.org/10.3390/molecules201219828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332199/
https://www.ncbi.nlm.nih.gov/pubmed/26690391
http://dx.doi.org/10.3390/molecules201219828

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