Pharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid Dehydrogenases

Computational methods are well-established tools in the drug discovery process and can be employed for a variety of tasks. Common applications include lead identification and scaffold hopping, as well as lead optimization by structure-activity relationship analysis and selectivity profiling. In addi...

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Detalles Bibliográficos
Autores principales: Kaserer, Teresa, Beck, Katharina R., Akram, Muhammad, Odermatt, Alex, Schuster, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332202/
https://www.ncbi.nlm.nih.gov/pubmed/26703541
http://dx.doi.org/10.3390/molecules201219880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332202/
https://www.ncbi.nlm.nih.gov/pubmed/26703541
http://dx.doi.org/10.3390/molecules201219880

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