Prazosin-Conjugated Matrices Based on Biodegradable Polymers and α-Amino Acids—Synthesis, Characterization, and in Vitro Release Study

Novel and promising macromolecular conjugates of the α1-adrenergic blocker prazosin were directly synthesized by covalent incorporation of the drug to matrices composed of biodegradable polymers and α-amino acids for the development of a polymeric implantable drug delivery carrier. The cyto- and gen...

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Detalles Bibliográficos
Autores principales: Oledzka, Ewa, Sawicka, Anna, Sobczak, Marcin, Nalecz-Jawecki, Grzegorz, Skrzypczak, Agata, Kolodziejski, Waclaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332215/
https://www.ncbi.nlm.nih.gov/pubmed/26274943
http://dx.doi.org/10.3390/molecules200814533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332215/
https://www.ncbi.nlm.nih.gov/pubmed/26274943
http://dx.doi.org/10.3390/molecules200814533

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