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Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker

A novel series of {4-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-1H-1,2,3-triazol-1-yl}alkylphosphonates and {4-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methyl]-1H-1,2,3-triazol-1-yl}alkylphosphonates as acyclic analogues of guanosine were synthesized and assessed for antiviral activity against a broa...

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Detalles Bibliográficos
Autores principales: Głowacka, Iwona E., Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Piotrowska, Dorota G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332235/
https://www.ncbi.nlm.nih.gov/pubmed/26501246
http://dx.doi.org/10.3390/molecules201018789