Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying

In this study, spray drying from aqueous solutions, using the surface-active agent sodium lauryl sulfate (SLS) as a solubilizer, was explored as a production method for co-amorphous simvastatin–lysine (SVS-LYS) at 1:1 molar mixtures, which previously have been observed to form a co-amorphous mixture...

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Detalles Bibliográficos
Autores principales: Craye, Goedele, Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas, Laitinen, Riikka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332242/
https://www.ncbi.nlm.nih.gov/pubmed/26633346
http://dx.doi.org/10.3390/molecules201219784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332242/
https://www.ncbi.nlm.nih.gov/pubmed/26633346
http://dx.doi.org/10.3390/molecules201219784

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