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Fluorescent Sensor for PH Monitoring Based on ani-Motif- – Switching Aptamer Containing a Tricyclic Cytosine Analogue (tC)
There are cytosine-rich regions in the genome that bind protons with high specificity. Thus protonated C-rich sequence may undergo folding to tetraplex structures called i-motifs. Therefore, one can regard such specific C-rich oligonucleotides as aptamers that recognize protons and undergo conformat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332284/ https://www.ncbi.nlm.nih.gov/pubmed/26473815 http://dx.doi.org/10.3390/molecules201018511 |