Neuroprotective Effects of Mitochondria-Targeted Plastoquinone and Thymoquinone in a Rat Model of Brain Ischemia/Reperfusion Injury

We explored the neuroprotective properties of natural plant-derived antioxidants plastoquinone and thymoquinone (2-demethylplastoquinone derivative) modified to be specifically accumulated in mitochondria. The modification was performed through chemical conjugation of the quinones with penetrating c...

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Detalles Bibliográficos
Autores principales: Silachev, Denis N., Plotnikov, Egor Y., Zorova, Ljubava D., Pevzner, Irina B., Sumbatyan, Natalia V., Korshunova, Galina A., Gulyaev, Mikhail V., Pirogov, Yury A., Skulachev, Vladimir P., Zorov, Dmitry B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332348/
https://www.ncbi.nlm.nih.gov/pubmed/26270657
http://dx.doi.org/10.3390/molecules200814487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332348/
https://www.ncbi.nlm.nih.gov/pubmed/26270657
http://dx.doi.org/10.3390/molecules200814487

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