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Synthesis and Evaluation of Selected Benzimidazole Derivatives as Potential Antimicrobial Agents

A library of 53 benzimidazole derivatives, with substituents at positions 1, 2 and 5, were synthesized and screened against a series of reference strains of bacteria and fungi of medical relevance. The SAR analyses of the most promising results showed that the antimicrobial activity of the compounds...

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Detalles Bibliográficos
Autores principales: Alasmary, Fatmah A. S., Snelling, Anna M., Zain, Mohammed E., Alafeefy, Ahmed M., Awaad, Amani S., Karodia, Nazira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332381/
https://www.ncbi.nlm.nih.gov/pubmed/26307956
http://dx.doi.org/10.3390/molecules200815206