Cargando…

Synthesis and Evaluation of Selected Benzimidazole Derivatives as Potential Antimicrobial Agents

A library of 53 benzimidazole derivatives, with substituents at positions 1, 2 and 5, were synthesized and screened against a series of reference strains of bacteria and fungi of medical relevance. The SAR analyses of the most promising results showed that the antimicrobial activity of the compounds...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alasmary, Fatmah A. S., Snelling, Anna M., Zain, Mohammed E., Alafeefy, Ahmed M., Awaad, Amani S., Karodia, Nazira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332381/ https://www.ncbi.nlm.nih.gov/pubmed/26307956 http://dx.doi.org/10.3390/molecules200815206

Ejemplares similares

Novel quinazoline and acetamide derivatives as safe anti-ulcerogenic agent and anti-ulcerative colitis activity
por: Alasmary, Fatmah A.S., et al.
Publicado: (2018)

Novel essential amino acid-sulfanilamide hybrid as safe anti-ulcerogenic agent with anti-helicobacter pylori activity
por: Awaad, Amani S., et al.
Publicado: (2017)

Anti-ulcerogenic and anti-ulcerative colitis (UC) activities of seven amines derivatives
por: Awaad, Amani S., et al.
Publicado: (2017)

Antitumor activity of extract and isolated compounds from Drechslera rostrata and Eurotium tonophilum
por: Alasmary, Fatmah A.S., et al.
Publicado: (2018)

Design and Synthesis of Benzimidazole-Chalcone Derivatives as Potential Anticancer Agents
por: Hsieh, Cheng-Ying, et al.
Publicado: (2019)

Evaluation of anti-ulcer and ulcerative colitis of Sonchus oleraceus L
por: Alothman, Esraa A., et al.
Publicado: (2018)

Anticancer effect of Cenchrus ciliaris L
por: Alothman, Esraa A., et al.
Publicado: (2018)

Synthesis, characterization and antimicrobial activity of some novel benzimidazole derivatives
por: Krishnanjaneyulu, Immadisetty Sri, et al.
Publicado: (2014)

Benzimidazole Schiff base derivatives: synthesis, characterization and antimicrobial activity
por: Fonkui, Thierry Youmbi, et al.
Publicado: (2019)

Design, synthesis and biological profile of heterocyclic benzimidazole analogues as prospective antimicrobial and antiproliferative agents
por: Tahlan, Sumit, et al.
Publicado: (2019)

New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase
por: Alasmary, Fatmah A. S., et al.
Publicado: (2017)

Antimicrobial, antioxidant and anticancer activities of Laurencia catarinensis, Laurencia majuscula and Padina pavonica extracts
por: Al-Enazi, Nouf M., et al.
Publicado: (2018)

Zinc Coordination Compounds with Benzimidazole Derivatives: Synthesis, Structure, Antimicrobial Activity and Potential Anticancer Application
por: Raducka, Anita, et al.
Publicado: (2022)

Comparative nutritional value and antimicrobial activities between three Euphorbia species growing in Saudi Arabia
por: Awaad, Amani S., et al.
Publicado: (2017)

Recent achievements in the synthesis of benzimidazole derivatives
por: Chung, Nguyen Thi, et al.
Publicado: (2023)

Synthesis of Antimicrobial Benzimidazole–Pyrazole Compounds and Their Biological Activities
por: Marinescu, Maria
Publicado: (2021)

Synthesis and Biological Evaluation of Benzimidazole Phenylhydrazone Derivatives as Antifungal Agents against Phytopathogenic Fungi
por: Wang, Xing, et al.
Publicado: (2016)

Novel Adamantane-Linked Isothiourea Derivatives as Potential Chemotherapeutic Agents: Synthesis, Structural Insights, and Antimicrobial/Anti-Proliferative Profiles
por: Al-Omary, Fatmah A. M., et al.
Publicado: (2023)

Novel Benzothiazole, Benzimidazole and Benzoxazole Derivatives as Potential Antitumor Agents: Synthesis and Preliminary in Vitro Biological Evaluation
por: Xiang, Pu, et al.
Publicado: (2012)

Evaluation of the chemical constituents and potential biological activities of Cunninghamella blakesleeana
por: Alasmary, Fatemah A., et al.
Publicado: (2020)

Synthesis of Benzimidazole-Sulfonyl Derivatives and Their Biological Activities
por: Mulugeta, Endale, et al.
Publicado: (2022)

Benzimidazole-Triazole Hybrids as Antimicrobial and Antiviral Agents: A Systematic Review
por: Marinescu, Maria
Publicado: (2023)

Synthesis, Characterization, and Biological Evaluation of Benzimidazole Derivatives as Potential Anxiolytics
por: Nannapaneni, DT, et al.
Publicado: (2010)

Metal complexes of benzimidazole-derived as potential anti-cancer agents: synthesis, characterization, combined experimental and computational studies
por: Nguyen, Van-Thanh, et al.
Publicado: (2022)

Synthesis of Benzimidazole-1,2,4-triazole Derivatives as Potential Antifungal Agents Targeting 14α-Demethylase
por: Güzel, Emir, et al.
Publicado: (2023)

Symmetric molecules with 1,4-triazole moieties as potent inhibitors of tumour-associated lactate dehydrogenase-A
por: Altamimi, Abdul-Malek S., et al.
Publicado: (2017)

Synthesis and Antiproliferative Activities of Benzimidazole-Based Sulfide and Sulfoxide Derivatives
por: Gaballah, Samir T., et al.
Publicado: (2016)

Novel 2-Thioxanthine and Dipyrimidopyridine Derivatives: Synthesis and Antimicrobial Activity †
por: El-kalyoubi, Samar, et al.
Publicado: (2015)

Evaluation of antimicrobial activity of secondary metabolites of fungi isolated from Sultanate Oman soil
por: Alkhulaifi, Manal M., et al.
Publicado: (2019)

Design, synthesis, bio-evaluation, and in silico studies of some N-substituted 6-(chloro/nitro)-1H-benzimidazole derivatives as antimicrobial and anticancer agents
por: Pham, Em Canh, et al.
Publicado: (2022)

Antituberculosis: Synthesis and Antimycobacterial Activity of Novel Benzimidazole Derivatives
por: Keng Yoon, Yeong, et al.
Publicado: (2013)

Synthesis and antifungal activity of benzimidazole, benzotriazole and aminothiazole derivatives
por: Khabnadideh, S., et al.
Publicado: (2012)

Synthesis and Antimicrobial Activity Evaluation of Homodrimane Sesquiterpenoids with a Benzimidazole Unit
por: Lungu, Lidia, et al.
Publicado: (2023)

Selective and eco-friendly procedures for the synthesis of benzimidazole derivatives. The role of the Er(OTf)(3) catalyst in the reaction selectivity
por: Herrera Cano, Natividad, et al.
Publicado: (2016)

N,2,6-Trisubstituted 1H-benzimidazole derivatives as a new scaffold of antimicrobial and anticancer agents: design, synthesis, in vitro evaluation, and in silico studies
por: Pham, Em Canh, et al.
Publicado: (2022)

Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents
por: Mohamed, Mosaad S., et al.
Publicado: (2010)

Design, synthesis and evaluation of carbazole derivatives as potential antimicrobial agents
por: Xue, Yi-Jie, et al.
Publicado: (2021)

Novel coumarin–benzimidazole derivatives as antioxidants and safer anti-inflammatory agents
por: Arora, Radha Krishan, et al.
Publicado: (2014)

Benzimidazole derivatives: search for GI-friendly anti-inflammatory analgesic agents
por: Gaba, Monika, et al.
Publicado: (2015)

Design, Synthesis, and Biological Evaluation of Benzimidazole Derivatives as Potential Lassa Virus Inhibitors
por: Chen, Jinwei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nio5har5pm30k9be2080mcp4g1