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An Effective Synthesis Method for Tilorone Dihydrochloride with Obvious IFN-α Inducing Activity

Tilorone dihydrochloride (1) has great potential for inducing interferon against pathogenic infection. In this paper, we describe a convenient preparation method for 2,7-dihydroxyfluoren-9-one (2), which is a usual pharmaceutical intermediate for preparing tilorone dihydrochloride (1). In the novel...

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Detalles Bibliográficos
Autores principales: Zhang, Junren, Yao, Qizheng, Liu, Zuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332401/
https://www.ncbi.nlm.nih.gov/pubmed/26633340
http://dx.doi.org/10.3390/molecules201219781