Virtual Screening and Molecular Dynamics Study of Potential Negative Allosteric Modulators of mGluR1 from Chinese Herbs

The metabotropic glutamate subtype 1 (mGluR1), a member of the metabotropic glutamate receptors, is a therapeutic target for neurological disorders. However, due to the lower subtype selectivity of mGluR1 orthosteric compounds, a new targeted strategy, known as allosteric modulators research, is nee...

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Detalles Bibliográficos
Autores principales: Jiang, Ludi, Zhang, Xianbao, Chen, Xi, He, Yusu, Qiao, Liansheng, Zhang, Yanling, Li, Gongyu, Xiang, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332408/
https://www.ncbi.nlm.nih.gov/pubmed/26184151
http://dx.doi.org/10.3390/molecules200712769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332408/
https://www.ncbi.nlm.nih.gov/pubmed/26184151
http://dx.doi.org/10.3390/molecules200712769

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