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Validated LC-MS/MS Method for the Determination of Scopoletin in Rat Plasma and Its Application to Pharmacokinetic Studies

A rapid, sensitive and selective liquid chromatography-electrospray ionization-tandem mass spectrometric method was developed and validated for the quantification of scopoletin in rat plasma. After the addition of the internal standard xanthotoxin, plasma samples were pretreated by a simple one-step...

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Detalles Bibliográficos
Autores principales: Zeng, Yingchun, Li, Sha, Wang, Xiaohong, Gong, Tao, Sun, Xun, Zhang, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332412/
https://www.ncbi.nlm.nih.gov/pubmed/26492227
http://dx.doi.org/10.3390/molecules201018988