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Validated LC-MS/MS Method for the Determination of Scopoletin in Rat Plasma and Its Application to Pharmacokinetic Studies
A rapid, sensitive and selective liquid chromatography-electrospray ionization-tandem mass spectrometric method was developed and validated for the quantification of scopoletin in rat plasma. After the addition of the internal standard xanthotoxin, plasma samples were pretreated by a simple one-step...
Autores principales: | Zeng, Yingchun, Li, Sha, Wang, Xiaohong, Gong, Tao, Sun, Xun, Zhang, Zhirong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332412/ https://www.ncbi.nlm.nih.gov/pubmed/26492227 http://dx.doi.org/10.3390/molecules201018988 |
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