Non-Nucleosidic Analogues of Polyaminonucleosides and Their Influence on Thermodynamic Properties of Derived Oligonucleotides

The rationale for the synthesis of cationic modified nucleosides is higher expected nuclease resistance and potentially better cellular uptake due to an overall reduced negative charge based on internal charge compensation. Due to the ideal distance between cationic groups, polyamines are perfect co...

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Detalles Bibliográficos
Autores principales: Brzezinska, Jolanta, Markiewicz, Wojciech T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332422/
https://www.ncbi.nlm.nih.gov/pubmed/26184145
http://dx.doi.org/10.3390/molecules200712652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332422/
https://www.ncbi.nlm.nih.gov/pubmed/26184145
http://dx.doi.org/10.3390/molecules200712652

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