Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents

New pyrazoline derivatives were synthesized and evaluated for their cytotoxic effects on AsPC-1 human pancreatic adenocarcinoma, U87 and U251 human glioblastoma cell lines. 1-[((5-(4-Methylphenyl)-1,3,4-oxadiazol-2-yl)thio)acetyl]-3-(2-thienyl)-5-(4-chlorophenyl)-2-pyrazoline (11) was found to be th...

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Detalles Bibliográficos
Autores principales: Karabacak, Muhammed, Altıntop, Mehlika Dilek, Çiftçi, Halil İbrahim, Koga, Ryoko, Otsuka, Masami, Fujita, Mikako, Özdemir, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332424/
https://www.ncbi.nlm.nih.gov/pubmed/26492233
http://dx.doi.org/10.3390/molecules201019066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332424/
https://www.ncbi.nlm.nih.gov/pubmed/26492233
http://dx.doi.org/10.3390/molecules201019066

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