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Syntheses of 4-Indolylquinoline Derivatives via Reductive Cyclization of Indolylnitrochalcone Derivatives by Fe/HCl

An easy and efficient procedure for the synthesis of 4-indolylquinoline derivatives is described. This process involves two steps, the first of which is the Michael addition of indole to nitrochalcones promoted by sulfamic acid under solvent free conditions and the second step is a reductive cycliza...

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Detalles Bibliográficos
Autores principales: Chen, Wen-Chang, Lin, Chan-Chieh, Kavala, Veerababurao, Kuo, Chun-Wei, Huang, Chia-Yu, Yao, Ching-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332431/
https://www.ncbi.nlm.nih.gov/pubmed/26694335
http://dx.doi.org/10.3390/molecules201219862