Synthesis of a Spirocyclic Oxetane-Fused Benzimidazole

A new synthesis of 2-oxa-7-azaspiro[3.5]nonane is described. Spirocyclic oxetanes, including 2-oxa-6-azaspiro[3.3]heptane were converted into o-cycloalkylaminoacetanilides for oxidative cyclizations using Oxone(®) in formic acid. The expanded spirocyclic oxetane successfully gave the [1,2-a] ring-fu...

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Detalles Bibliográficos
Autores principales: Gurry, Michael, McArdle, Patrick, Aldabbagh, Fawaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332447/
https://www.ncbi.nlm.nih.gov/pubmed/26263961
http://dx.doi.org/10.3390/molecules200813864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332447/
https://www.ncbi.nlm.nih.gov/pubmed/26263961
http://dx.doi.org/10.3390/molecules200813864

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