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Synthesis of a Spirocyclic Oxetane-Fused Benzimidazole
A new synthesis of 2-oxa-7-azaspiro[3.5]nonane is described. Spirocyclic oxetanes, including 2-oxa-6-azaspiro[3.3]heptane were converted into o-cycloalkylaminoacetanilides for oxidative cyclizations using Oxone(®) in formic acid. The expanded spirocyclic oxetane successfully gave the [1,2-a] ring-fu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332447/ https://www.ncbi.nlm.nih.gov/pubmed/26263961 http://dx.doi.org/10.3390/molecules200813864 |