Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani

[Image: see text] Visceral leishmaniasis (VL), caused by the protozoan parasites Leishmania donovani and L. infantum, is responsible for ∼30 000 deaths annually. Available treatments are inadequate, and there is a pressing need for new therapeutics. N-Myristoyltransferase (NMT) remains one of the fe...

Descripción completa

Detalles Bibliográficos
Autores principales: Corpas-Lopez, Victoriano, Moniz, Sonia, Thomas, Michael, Wall, Richard J., Torrie, Leah S., Zander-Dinse, Dorothea, Tinti, Michele, Brand, Stephen, Stojanovski, Laste, Manthri, Sujatha, Hallyburton, Irene, Zuccotto, Fabio, Wyatt, Paul G., De Rycker, Manu, Horn, David, Ferguson, Michael A. J., Clos, Joachim, Read, Kevin D., Fairlamb, Alan H., Gilbert, Ian H., Wyllie, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332449/
https://www.ncbi.nlm.nih.gov/pubmed/30380837
http://dx.doi.org/10.1021/acsinfecdis.8b00226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332449/
https://www.ncbi.nlm.nih.gov/pubmed/30380837
http://dx.doi.org/10.1021/acsinfecdis.8b00226

Ejemplares similares