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Fluorination Effects on NOS Inhibitory Activity of Pyrazoles Related to Curcumin

A series of new (E)-3(5)-[β-(aryl)-ethenyl]-5(3)-phenyl-1H-pyrazoles bearing fluorine atoms at different positions of the aryl group have been synthesized starting from the corresponding β-diketones. All compounds have been characterized by elemental analysis, DSC as well as NMR ((1)H, (13)C, (19)F...

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Detalles Bibliográficos
Autores principales: Nieto, Carla I., Cabildo, María Pilar, Cornago, María Pilar, Sanz, Dionisia, Claramunt, Rosa M., Torralba, María Carmen, Torres, María Rosario, Elguero, José, García, José A., López, Ana, Acuña-Castroviejo, Darío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332466/
https://www.ncbi.nlm.nih.gov/pubmed/26343623
http://dx.doi.org/10.3390/molecules200915643