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Bilirubin Attenuates ER Stress-Mediated Inflammation, Escalates Apoptosis and Reduces Proliferation in the LS174T Colonic Epithelial Cell Line

Mildly elevated serum unconjugated bilirubin (UCB) concentrations are associated with protection against disease conditions underpinned by cellular and metabolic stress. To determine the potential therapeutic efficacy of UCB we tested it in an in vitro model of gut inflammation. Tunicamycin TUN (10...

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Detalles Bibliográficos
Autores principales: Gundamaraju, Rohit, Vemuri, Ravichandra, Chong, Wai Chin, Bulmer, Andrew Cameron, Eri, Rajaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332492/
https://www.ncbi.nlm.nih.gov/pubmed/30662337
http://dx.doi.org/10.7150/ijms.29134