Cargando…

Synthesis and Evaluation of a Rationally Designed Click-Based Library for G-Quadruplex Selective DNA Photocleavage

DNA containing repeating G-rich sequences can adopt higher-order structures known as G-quadruplexes (G4). These structures are believed to form within telomeres and the promoter regions of some genes, particularly in a number of proto-oncogenes, where they may play a role in regulating transcription...

Descripción completa

Detalles Bibliográficos
Autores principales: McBrayer, Dominic, Kerwin, Sean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332505/
https://www.ncbi.nlm.nih.gov/pubmed/26378509
http://dx.doi.org/10.3390/molecules200916446