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A Promising PET Tracer for Imaging of α(7) Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand

Changes in the expression of α(7) nicotinic acetylcholine receptors (α(7) nAChRs) in the human brain are widely assumed to be associated with neurological and neurooncological processes. Investigation of these receptors in vivo depends on the availability of imaging agents such as radioactively labe...

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Detalles Bibliográficos
Autores principales: Teodoro, Rodrigo, Scheunemann, Matthias, Deuther-Conrad, Winnie, Wenzel, Barbara, Fasoli, Francesca Maria, Gotti, Cecilia, Kranz, Mathias, Donat, Cornelius K., Patt, Marianne, Hillmer, Ansel, Zheng, Ming-Qiang, Peters, Dan, Steinbach, Jörg, Sabri, Osama, Huang, Yiyun, Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332508/
https://www.ncbi.nlm.nih.gov/pubmed/26473809
http://dx.doi.org/10.3390/molecules201018387