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A Promising PET Tracer for Imaging of α(7) Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand
Changes in the expression of α(7) nicotinic acetylcholine receptors (α(7) nAChRs) in the human brain are widely assumed to be associated with neurological and neurooncological processes. Investigation of these receptors in vivo depends on the availability of imaging agents such as radioactively labe...
Autores principales: | Teodoro, Rodrigo, Scheunemann, Matthias, Deuther-Conrad, Winnie, Wenzel, Barbara, Fasoli, Francesca Maria, Gotti, Cecilia, Kranz, Mathias, Donat, Cornelius K., Patt, Marianne, Hillmer, Ansel, Zheng, Ming-Qiang, Peters, Dan, Steinbach, Jörg, Sabri, Osama, Huang, Yiyun, Brust, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332508/ https://www.ncbi.nlm.nih.gov/pubmed/26473809 http://dx.doi.org/10.3390/molecules201018387 |
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