Leishmanicidal Activity of (+)-Phyllanthidine and the Phytochemical Profile of Margaritaria nobilis (Phyllanthaceae)

The effects of the Securinega alkaloid (+)-phyllanthidine on Leishmania (L.) amazonensis and the first chemical investigation of Margaritaria nobilis L.f. (Phyllanthaceae) are described. Treating the parasites with this alkaloid caused a dose-dependent reduction in promastigote growth of 67.68% (IC(...

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Detalles Bibliográficos
Autores principales: Moraes, Lienne S., Donza, Marcio R. H., Rodrigues, Ana Paula D., Silva, Bruno J. M., Brasil, Davi S. B., Zoghbi, Maria das Graças B., Andrade, Eloísa H. A., Guilhon, Giselle M. S. P., Silva, Edilene O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332510/
https://www.ncbi.nlm.nih.gov/pubmed/26690400
http://dx.doi.org/10.3390/molecules201219829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332510/
https://www.ncbi.nlm.nih.gov/pubmed/26690400
http://dx.doi.org/10.3390/molecules201219829

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