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Transcription factors STAT-4, STAT-6 and CREB regulate Th1/Th2 response in leprosy patients: effect of M. leprae antigens

BACKGROUND: Leprosy is an ideal human disease to study T cell regulation as patients show correlation between cytokine skewed Th1-Th2 responses and clinical forms of the disease. The Role of transcription factors on the modulation of Th1 and Th2 responses by M. leprae antigens has not been adequatel...

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Detalles Bibliográficos
Autores principales: Upadhyay, Rajni, Dua, Bhavyata, Sharma, Bhawna, Natrajan, Mohan, Jain, Ajai Kumar, Kithiganahalli Narayanaswamy, Balaji, Joshi, Beenu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332553/
https://www.ncbi.nlm.nih.gov/pubmed/30642265
http://dx.doi.org/10.1186/s12879-018-3601-z