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Transcription factors STAT-4, STAT-6 and CREB regulate Th1/Th2 response in leprosy patients: effect of M. leprae antigens
BACKGROUND: Leprosy is an ideal human disease to study T cell regulation as patients show correlation between cytokine skewed Th1-Th2 responses and clinical forms of the disease. The Role of transcription factors on the modulation of Th1 and Th2 responses by M. leprae antigens has not been adequatel...
Autores principales: | Upadhyay, Rajni, Dua, Bhavyata, Sharma, Bhawna, Natrajan, Mohan, Jain, Ajai Kumar, Kithiganahalli Narayanaswamy, Balaji, Joshi, Beenu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332553/ https://www.ncbi.nlm.nih.gov/pubmed/30642265 http://dx.doi.org/10.1186/s12879-018-3601-z |
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