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The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer

BACKGROUND: Head and Neck Squamous Cell Carcinoma (HNSCC) tumors are often resistant to therapies. Therefore searching for predictive markers and new targets for treatment in clinically relevant in vitro tumor models is essential. Five HNSCC-derived cell lines were used to assess the effect of 3D cu...

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Detalles Bibliográficos
Autores principales: Melissaridou, Styliani, Wiechec, Emilia, Magan, Mustafa, Jain, Mayur Vilas, Chung, Man Ki, Farnebo, Lovisa, Roberg, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332598/
https://www.ncbi.nlm.nih.gov/pubmed/30651721
http://dx.doi.org/10.1186/s12935-019-0733-1