CYR61 triggers osteosarcoma metastatic spreading via an IGF1Rβ-dependent EMT-like process

BACKGROUND: Osteosarcoma is the most prevalent primary bone malignancy in children and young adults. These tumors are highly metastatic, leading to poor outcome. We previously demonstrated that Cysteine-rich protein 61 (CYR61/CCN1) expression level is correlated to osteosarcoma aggressiveness in pre...

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Detalles Bibliográficos
Autores principales: Habel, Nadia, Stefanovska, Bojana, Carène, Dimitri, Patiño-Garcia, Ana, Lecanda, Fernando, Fromigué, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332662/
https://www.ncbi.nlm.nih.gov/pubmed/30642298
http://dx.doi.org/10.1186/s12885-019-5282-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332662/
https://www.ncbi.nlm.nih.gov/pubmed/30642298
http://dx.doi.org/10.1186/s12885-019-5282-4

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