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Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain

BACKGROUND: Dissemination of breast cancers to the brain is associated with poor patient outcome and limited therapeutic options. In this study we sought to identify novel regulators of brain metastasis by profiling mouse mammary carcinoma cells spontaneously metastasising from the primary tumour in...

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Detalles Bibliográficos
Autores principales: Kijewska, Magdalena, Viski, Carmen, Turrell, Frances, Fitzpatrick, Amanda, van Weverwijk, Antoinette, Gao, Qiong, Iravani, Marjan, Isacke, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332688/
https://www.ncbi.nlm.nih.gov/pubmed/30642388
http://dx.doi.org/10.1186/s13058-018-1093-9