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Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy

BACKGROUND: Chemoradiotherapy (CRT) remains one of the most common cancer treatment modalities, and recent data suggest that CRT is maximally effective when there is generation of an anti-tumoral immune response. However, CRT has also been shown to promote immunosuppressive mechanisms which must be...

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Detalles Bibliográficos
Autores principales: Hanoteau, Aurelie, Newton, Jared M., Krupar, Rosemarie, Huang, Chen, Liu, Hsuan-Chen, Gaspero, Angelina, Gartrell, Robyn D., Saenger, Yvonne M., Hart, Thomas D., Santegoets, Saskia J., Laoui, Damya, Spanos, Chad, Parikh, Falguni, Jayaraman, Padmini, Zhang, Bing, Van der Burg, Sjoerd H., Van Ginderachter, Jo A., Melief, Cornelis J. M., Sikora, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332704/
https://www.ncbi.nlm.nih.gov/pubmed/30646957
http://dx.doi.org/10.1186/s40425-018-0485-9