Cargando…

An IgM antibody targeting the receptor binding site of influenza B blocks viral infection with great breadth and potency

Broadly neutralizing antibodies (bnAbs) targeting the receptor binding site (RBS) of hemagglutinin (HA) have potential for developing into powerful anti-influenza agents. Several previously reported influenza B bnAbs are nevertheless unable to neutralize a portion of influenza B virus variants. HA-s...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Chenguang, Zhang, Minwei, Chen, Yuanzhi, Zhang, Limin, Wang, Guosong, Chen, Junyu, Chen, Siyuan, Li, Zizhen, Wei, Feixue, Chen, Jing, Yang, Kunyu, Guo, Shuxin, Wang, Yujing, Zheng, Qingbing, Yu, Hai, Luo, Wenxin, Zhang, Jun, Chen, Honglin, Chen, Yixin, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332795/
https://www.ncbi.nlm.nih.gov/pubmed/30662563
http://dx.doi.org/10.7150/thno.28434