Cargando…
An IgM antibody targeting the receptor binding site of influenza B blocks viral infection with great breadth and potency
Broadly neutralizing antibodies (bnAbs) targeting the receptor binding site (RBS) of hemagglutinin (HA) have potential for developing into powerful anti-influenza agents. Several previously reported influenza B bnAbs are nevertheless unable to neutralize a portion of influenza B virus variants. HA-s...
Autores principales: | Shen, Chenguang, Zhang, Minwei, Chen, Yuanzhi, Zhang, Limin, Wang, Guosong, Chen, Junyu, Chen, Siyuan, Li, Zizhen, Wei, Feixue, Chen, Jing, Yang, Kunyu, Guo, Shuxin, Wang, Yujing, Zheng, Qingbing, Yu, Hai, Luo, Wenxin, Zhang, Jun, Chen, Honglin, Chen, Yixin, Xia, Ningshao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332795/ https://www.ncbi.nlm.nih.gov/pubmed/30662563 http://dx.doi.org/10.7150/thno.28434 |
Ejemplares similares
-
Development of functional antibodies against influenza B virus by activation-induced cytidine deaminase in hybridoma cells
por: Chen, Yuanzhi, et al.
Publicado: (2022) -
Vaccination with Deglycosylated Modified Hemagglutinin Broadly Protects against Influenza Virus Infection in Mice and Ferrets
por: Zhang, Limin, et al.
Publicado: (2022) -
A Hemagglutinin Stem Vaccine Designed Rationally by AlphaFold2 Confers Broad Protection against Influenza B Infection
por: Zeng, Dian, et al.
Publicado: (2022) -
Antibody engineering for increased potency, breadth and half-life
por: Sievers, Stuart A., et al.
Publicado: (2015) -
Diet Breadth Mediates the Prey Specificity of Venom Potency in Snakes
por: Lyons, Keith, et al.
Publicado: (2020)