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Enhancement of mitochondrial ROS accumulation and radiotherapeutic efficacy using a Gd-doped titania nanosensitizer

Radiotherapy is an extensively used treatment modality in the clinic and can kill malignant cells by generating cytotoxic reactive oxygen species (ROS). Unfortunately, excessive dosages of radiation are typically required because only a small proportion of the radiative energy is adsorbed by the sof...

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Detalles Bibliográficos
Autores principales: Chen, Yuanyuan, Li, Na, Wang, Jianbo, Zhang, Xia, Pan, Wei, Yu, Longhai, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332802/
https://www.ncbi.nlm.nih.gov/pubmed/30662560
http://dx.doi.org/10.7150/thno.28033