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Emerging roles of gap junction proteins connexins in cancer metastasis, chemoresistance and clinical application
Connexin, a four-pass transmembrane protein, contributes to assembly of gap junctions among neighboring cells and thus facilitates gap junctional intercellular communication (GJIC). Traditionally, the roles of connexins were thought to mediate formation of hemichannels and GJIC assembly for transpor...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332853/ https://www.ncbi.nlm.nih.gov/pubmed/30642339 http://dx.doi.org/10.1186/s12929-019-0497-x |