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Emerging roles of gap junction proteins connexins in cancer metastasis, chemoresistance and clinical application

Connexin, a four-pass transmembrane protein, contributes to assembly of gap junctions among neighboring cells and thus facilitates gap junctional intercellular communication (GJIC). Traditionally, the roles of connexins were thought to mediate formation of hemichannels and GJIC assembly for transpor...

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Detalles Bibliográficos
Autores principales: Wu, Jun-I, Wang, Lu-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332853/
https://www.ncbi.nlm.nih.gov/pubmed/30642339
http://dx.doi.org/10.1186/s12929-019-0497-x