Exosomal miR-196a derived from cancer-associated fibroblasts confers cisplatin resistance in head and neck cancer through targeting CDKN1B and ING5

BACKGROUND: Cisplatin resistance is a major challenge for advanced head and neck cancer (HNC). Understanding the underlying mechanisms and developing effective strategies against cisplatin resistance are highly desired in the clinic. However, how tumor stroma modulates HNC growth and chemoresistance...

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Detalles Bibliográficos
Autores principales: Qin, Xing, Guo, Haiyan, Wang, Xiaoning, Zhu, Xueqin, Yan, Ming, Wang, Xu, Xu, Qin, Shi, Jianbo, Lu, Eryi, Chen, Wantao, Zhang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332863/
https://www.ncbi.nlm.nih.gov/pubmed/30642385
http://dx.doi.org/10.1186/s13059-018-1604-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332863/
https://www.ncbi.nlm.nih.gov/pubmed/30642385
http://dx.doi.org/10.1186/s13059-018-1604-0

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