Cargando…

Norfluoxetine Prevents Degeneration of Dopamine Neurons by Inhibiting Microglia-Derived Oxidative Stress in an MPTP Mouse Model of Parkinson's Disease

Neuroinflammation is the neuropathological feature of Parkinson's disease (PD) and causes microglial activation and activated microglia-derived oxidative stress in the PD patients and PD animal models, resulting in neurodegeneration. The present study examined whether norfluoxetine (a metabolit...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Kyung In, Chung, Young Cheul, Jin, Byung Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332876/
https://www.ncbi.nlm.nih.gov/pubmed/30692871
http://dx.doi.org/10.1155/2018/4591289