Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling

The present study examined the effects of tetrandrine suppressing proliferation, targeting LC3, p62, and Beclin-1 autophagy genes by inhibiting PI3K/AKT/mTOR signaling in Triple-negative breast cancer (TNBC) MDA-MB-231 cell. Cell viability and apoptosis were evaluated by MTT and Annexin-V/PI double...

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Detalles Bibliográficos
Autores principales: Guo, Yubo, Pei, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332987/
https://www.ncbi.nlm.nih.gov/pubmed/30713576
http://dx.doi.org/10.1155/2019/7517431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332987/
https://www.ncbi.nlm.nih.gov/pubmed/30713576
http://dx.doi.org/10.1155/2019/7517431

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